Impact of enriched environment on production of tau, amyloid precursor protein and, amyloid-beta peptide in high-fat and high-sucrose-fed rats


SELVİ Y., GERGERLİOĞLU H. S. , Akbaba N., Oz M., Kandeger A., Demir E. A. , ...More

ACTA NEUROPSYCHIATRICA, vol.29, no.5, pp.291-298, 2017 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 29 Issue: 5
  • Publication Date: 2017
  • Doi Number: 10.1017/neu.2016.63
  • Title of Journal : ACTA NEUROPSYCHIATRICA
  • Page Numbers: pp.291-298

Abstract

Objective: The Western-type diet is associated with an elevated risk of Alzheimer's disease and other milder forms of cognitive impairment. The aim of the present study was to investigate the effects of the environmental enrichment on amyloid and tau pathology in high-fat and high-sucrose-fed rats.