Diş Çürüğü Ve Kanabinoid Bileşikleri Arasındaki Ilişki

Cannabis sativa (Indian hemp) was first used in China in 2700 BC and has a long history in Asian, African, and Indian medicine. Medical use of cannabis continued until the 1940s, and restrictions were imposed in many countries due to potential problems associated with its psychoactive properties. Despite these restrictions, cannabis has been studied in scientific studies, and interest in cannabis has increased.

The term cannabinoid refers to a broad class of compounds that includes phytocannabinoids derived from the cannabis plant, naturally occurring endocannabinoids within the human body, and cannabinoids produced synthetically. Growing scientific interest in recent years has highlighted their potential application in dentistry. Beyond their role in preventing dental caries, cannabinoids have been explored for the management of tooth pain, periodontal disease, infections of the gums and salivary glands, malignancies affecting the oral cavity and salivary tissues, burning mouth syndrome, and dental-related anxiety.

Cannabinoids exhibit antimicrobial, antibiofilm, anti-inflammatory, analgesic, and antioxidant properties, making them promising candidates for both the prevention and treatment of dental caries. Current literature emphasizes the therapeutic potential of non- psychoactive cannabinoids such as cannabidiol (CBD), cannabigerol (CBG), and cannabichromene (CBC) in promoting oral health. Although these agents have been examined in a growing number of recent studies, additional research is still required to clarify their mechanisms of action and evaluate possible adverse effects.