Recurrent pregnancy loss and association with anti phospho lipid syndrome


Kara M., Caglayan E. K., Gunaydin I.

PAKISTAN JOURNAL OF MEDICAL SCIENCES, cilt.27, sa.3, ss.682-685, 2011 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 27 Sayı: 3
  • Basım Tarihi: 2011
  • Dergi Adı: PAKISTAN JOURNAL OF MEDICAL SCIENCES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.682-685
  • Yozgat Bozok Üniversitesi Adresli: Evet

Özet

Recurrent miscarriage, the occurrence of three consecutive first-trimester losses of pregnancy, affects 1-3 % of pregnant women. The purported causes of recurrent miscarriage include chromosomal abnormalities, thrombophilia, metabolic disorders, anatomical and immunological disturbances. At present, the only recommended investigations are testing for lupus anticoagulant and anticardiolipin antibody levels to diagnose the antiphospholipid syndrome, an acquired thrombophilia and the karyotyping of both parents for chromosomal abnormalities. The Antiphospholipid Syndrome (APS) is an autoimmune disorder characterized by thrombosis, recurrent loss of pregnancy combined with laboratory tests that indicate the presence of antibodies against phospholipid binding proteins.