The effect of systemic isotretinoin treatment on skin biophysical parameters among patients with acne vulgaris

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ÇÖLGEÇEN E., Ozyurt K., Kesikoglu A. F.

TURKISH JOURNAL OF MEDICAL SCIENCES, cilt.46, sa.6, ss.1641-1644, 2016 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 46 Sayı: 6
  • Basım Tarihi: 2016
  • Doi Numarası: 10.3906/sag-1507-31
  • Dergi Adı: TURKISH JOURNAL OF MEDICAL SCIENCES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.1641-1644
  • Anahtar Kelimeler: Acne vulgaris, isotretinoin, retinoids, biophysical skin parameters, TRANSEPIDERMAL WATER-LOSS, THERAPY, HYDRATION
  • Yozgat Bozok Üniversitesi Adresli: Evet

Özet

Background/aim: Systemic isotretinoin has been widely considered an effective and safe medical treatment for severe and refractory acne for nearly 3 decades. However, it also appears to cause undesirable cutaneous side effects. The aim of this study was to prospectively measure biophysical parameters of skin function among patients with acne vulgaris before and after 3 months of isotretinoin therapy, including pH, temperature, sebum content, skin hydration, and transepidermal water loss.