The effect of stereoisomerism on the 4D-QSAR study of some dipeptidyl boron derivatives

Catalkaya S., Sabanci N., Yavuz S., SARIPINAR E.

COMPUTATIONAL BIOLOGY AND CHEMISTRY, vol.84, 2020 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 84
  • Publication Date: 2020
  • Doi Number: 10.1016/j.compbiolchem.2019.107190
  • Journal Name: COMPUTATIONAL BIOLOGY AND CHEMISTRY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Applied Science & Technology Source, BIOSIS, Biotechnology Research Abstracts, Chemical Abstracts Core, Chimica, Compendex, Computer & Applied Sciences, EMBASE, INSPEC, MEDLINE, zbMATH
  • Yozgat Bozok University Affiliated: Yes

Abstract

The electron conformational genetic algorithm (EC-GA) method had been employed by distinguishing between enantiomers for the first time as a 4D-QSAR approach to reveal the pharmacophore (Pha) and to predict the bioactivity of the dipeptidyl boron compounds.