The relationship between oxidative stress and preeclampsia. The serum ischemia-modified albumin levels and thiol/disulfide homeostasis


ONAT T. , AYDOĞAN KIRMIZI D. , BAŞER E. , Ercan M., DEMİR ÇALTEKİN M. , Yalcin S., ...More

TURKISH JOURNAL OF OBSTETRICS AND GYNECOLOGY, vol.17, no.2, pp.102-107, 2020 (Journal Indexed in ESCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 17 Issue: 2
  • Publication Date: 2020
  • Doi Number: 10.4274/tjod.galenos.2020.23682
  • Title of Journal : TURKISH JOURNAL OF OBSTETRICS AND GYNECOLOGY
  • Page Numbers: pp.102-107
  • Keywords: Preeclampsia, hypertension, oxidative stress, thiol/disulfide, ischemia-modified albumin, REDOX SYSTEMS, ACTIVIN-A, PREGNANCY, MARKER, ROLES, ASSAY

Abstract

Objective: Preeclampsia (PE) is a dangerous complication of pregnancy and still a major cause of maternal-fetal morbidity and mortality. Its etiology remains largely unknown, but researchers have suggested oxidative stress-mediated inflammation for the same. The purpose of this study is to investigate the relationship between oxidative stress and PE as well as the usability of oxidative stress indicators such as serum ischemia modified albumin (IMA) levels and thio/disulfide balance in the prediction of PE.