Increased level of plasma salusin-alpha and salusin-beta in patients with multiple sclerosis

ÇAKIR M., SABAH ÖZCAN S., SAÇMACI H.

MULTIPLE SCLEROSIS AND RELATED DISORDERS, vol.30, pp.76-80, 2019 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 30
  • Publication Date: 2019
  • Doi Number: 10.1016/j.msard.2019.02.003
  • Journal Name: MULTIPLE SCLEROSIS AND RELATED DISORDERS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.76-80
  • Keywords: Salusin-alpha, Salusin-beta, Multiple sclerosis, Relapsing-Remitting Multiple Sclerosis, PARAVENTRICULAR NUCLEUS, BLOOD-PRESSURE, SERUM, BIOMARKERS, NEURODEGENERATION, HYPERTENSION, INFLAMMATION, PEPTIDES, CELLS
  • Yozgat Bozok University Affiliated: Yes

Abstract

Background: Multiple Sclerosis (MS) is a potentially progressive autoimmune disorder of the central nervous system. The pathology of MS is characterized by inflammation, demyelination, reactive gliosis and neuronal damage. Salusin-alpha and salusin-beta have been shown to be widely expressed in many tissues, including the central nervous system. In our study, we investigated whether salusin-alpha and salusin-beta peptides had a relation with inflammation and whether it is related to Relapsing-Remitting Multiple Sclerosis (RRMS) disease.