High serum levels of neopterin in patients with Crimean-Congo hemorrhagic fever and its relation with mortality


Pinar O., Ozgur A. E. , Esragul A., Halil Y., Gulcan K. Y. , Ayse E. , ...More

JOURNAL OF INFECTION, vol.56, no.5, pp.366-370, 2008 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 56 Issue: 5
  • Publication Date: 2008
  • Doi Number: 10.1016/j.jinf.2008.03.006
  • Title of Journal : JOURNAL OF INFECTION
  • Page Numbers: pp.366-370
  • Keywords: neopterin, Crimean-Congo hemorrhagic fever, mortality, risk factors, VIRUS, INFECTION, SEVERITY, MARKER

Abstract

Objective: Neopterin is generated and released in increased amounts by macrophages upon activation by interferon-gamma during cellular immune response. In this study, we aimed to investigate serum neopterin levels in patients with Crimean-Congo hemorrhagic fever (CCHF) and its clinical significance as a predictor factor of mortality.