High serum levels of neopterin in patients with Crimean-Congo hemorrhagic fever and its relation with mortality

Pinar O., Ozgur A. E., Esragul A., Halil Y., Gulcan K. Y., Ayse E., ...More

JOURNAL OF INFECTION, vol.56, no.5, pp.366-370, 2008 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 56 Issue: 5
  • Publication Date: 2008
  • Doi Number: 10.1016/j.jinf.2008.03.006
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.366-370
  • Keywords: neopterin, Crimean-Congo hemorrhagic fever, mortality, risk factors, VIRUS, INFECTION, SEVERITY, MARKER
  • Yozgat Bozok University Affiliated: No


Objective: Neopterin is generated and released in increased amounts by macrophages upon activation by interferon-gamma during cellular immune response. In this study, we aimed to investigate serum neopterin levels in patients with Crimean-Congo hemorrhagic fever (CCHF) and its clinical significance as a predictor factor of mortality.