High serum levels of neopterin in patients with Crimean-Congo hemorrhagic fever and its relation with mortality

Pinar, Onguru; Ozgur, Akgul; Esragul, Akinci; Halil, Yaman; Gulcan, Kurt; Ayse, AYŞE; Nurhayat, Bayazit; Hurrem, Bodur; Kemal, Erbil; Han, Acikel; Aydin, Cevik

doi:10.1016/j.jinf.2008.03.006

High serum levels of neopterin in patients with Crimean-Congo hemorrhagic fever and its relation with mortality

Pinar O., Ozgur A. E., Esragul A., Halil Y., Gulcan K. Y., Ayse E., ...Daha Fazla

JOURNAL OF INFECTION, cilt.56, sa.5, ss.366-370, 2008 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 56 Sayı: 5
Basım Tarihi: 2008
Doi Numarası: 10.1016/j.jinf.2008.03.006
Dergi Adı: JOURNAL OF INFECTION
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.366-370
Anahtar Kelimeler: neopterin, Crimean-Congo hemorrhagic fever, mortality, risk factors, VIRUS, INFECTION, SEVERITY, MARKER
Yozgat Bozok Üniversitesi Adresli: Hayır

Özet

Objective: Neopterin is generated and released in increased amounts by macrophages upon activation by interferon-gamma during cellular immune response. In this study, we aimed to investigate serum neopterin levels in patients with Crimean-Congo hemorrhagic fever (CCHF) and its clinical significance as a predictor factor of mortality.