Resveratrol Treatment Prevents Hippocampal Neurodegeneration in a Rodent Model of Traumatic Brain Injury

Atalay, Tugay; Gülşen, İsmail; Çölçimen, Neşe; Alp, Hamit; Sosuncu, Enver; Alaca, Ilker; AK, HAKAN; Rağbetli, Murat

doi:10.5137/1019-5149.jtn.17249-16.2

Resveratrol Treatment Prevents Hippocampal Neurodegeneration in a Rodent Model of Traumatic Brain Injury

Atalay T., Gülşen İ., Çölçimen N., Alp H. H., Sosuncu E., Alaca I., ...Daha Fazla

TURKISH NEUROSURGERY, cilt.27, sa.6, ss.924-930, 2017 (SCI-Expanded, Scopus, TRDizin)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 27 Sayı: 6
Basım Tarihi: 2017
Doi Numarası: 10.5137/1019-5149.jtn.17249-16.2
Dergi Adı: TURKISH NEUROSURGERY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
Sayfa Sayıları: ss.924-930
Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
Yozgat Bozok Üniversitesi Adresli: Evet

Özet

AIM: Traumatic brain injury (TBI) is a complex process. Increasing evidence has demonstrated that reactive oxygen species contribute to brain injury. Resveratrol (RVT) which exhibits significant antioxidant properties, is neuroprotective against excitotoxicity, ischemia, and hypoxia. The aim of this study was to evaluate the neuroprotective effects of RVT on the hippocampus of a rat model of TBI.