Resveratrol Treatment Prevents Hippocampal Neurodegeneration in a Rodent Model of Traumatic Brain Injury

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Atalay T., Gülşen İ., Çölçimen N., Alp H. H. , Sosuncu E., Alaca I., ...More

TURKISH NEUROSURGERY, vol.27, no.6, pp.924-930, 2017 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 27 Issue: 6
  • Publication Date: 2017
  • Doi Number: 10.5137/1019-5149.jtn.17249-16.2
  • Title of Journal : TURKISH NEUROSURGERY
  • Page Numbers: pp.924-930

Abstract

AIM: Traumatic brain injury (TBI) is a complex process. Increasing evidence has demonstrated that reactive oxygen species contribute to brain injury. Resveratrol (RVT) which exhibits significant antioxidant properties, is neuroprotective against excitotoxicity, ischemia, and hypoxia. The aim of this study was to evaluate the neuroprotective effects of RVT on the hippocampus of a rat model of TBI.