EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES, vol.19, no.15, pp.2866-2874, 2015 (Journal Indexed in SCI)
Article / Article
Title of Journal :
EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES
Electrophysiology, Orchiectomy, Rat, 17 beta estradiol, Androgen depletion, GENDER-DIFFERENCES, 17-BETA-ESTRADIOL, HEART, TESTOSTERONE, REPLACEMENT, WOMEN, RISK, MEN
OBJCTIVE: Although the testosterone has a protective effect on heart, patients having maximal androgen blockade due to prostate cancer resembles endothelial dysfunction and cardiac problems when compared to normal population. We aimed to test the effect of 17 beta estradiol on the orchiectomized male rat heart electrophysiology and ion channel expression levels.