Revisiting the role of neurotransmitters in epilepsy: An updated review

Akyuz E., Polat A. K., Eroglu E., Kullu I., Angelopoulou E., Paudel Y. N.

LIFE SCIENCES, vol.265, 2021 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Review
  • Volume: 265
  • Publication Date: 2021
  • Doi Number: 10.1016/j.lfs.2020.118826
  • Journal Name: LIFE SCIENCES
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, CAB Abstracts, Chimica, EMBASE, MEDLINE, Veterinary Science Database
  • Yozgat Bozok University Affiliated: Yes

Abstract

Epilepsy is a neumlogicaldisorder characterized by persistent predisposition to recurrent seizurescaused by abnormal neuronal activity in the brain. Epileptic seizures maydevelop due to a relative imbalance of excitatory and inhibitory neurotransmitters. Expressional alterations of receptors and ion channels activated by neurotransmitters can lead to epilepsy pathogenesis.