Urapidil alleviates ovarian torsion detorsion injury via regulating oxidative stress, apoptosis, autophagia, and inflammation

GÜLER, Mustafa; TANYELİ, Ayhan; Erdogan, Derya; ERASLAN, ERSEN; ÇOMAKLI, Selim; Polat, Elif; DOĞANAY, SONGÜL

doi:10.22038/ijbms.2021.57196.12736

Urapidil alleviates ovarian torsion detorsion injury via regulating oxidative stress, apoptosis, autophagia, and inflammation

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GÜLER M. C., TANYELİ A., Erdogan D. G., ERASLAN E., ÇOMAKLI S., Polat E., ...More

IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, vol.24, no.7, pp.935-942, 2021 (SCI-Expanded)

Publication Type: Article / Article
Volume: 24 Issue: 7
Publication Date: 2021
Doi Number: 10.22038/ijbms.2021.57196.12736
Journal Name: IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, CAB Abstracts, EMBASE, Index Islamicus, Veterinary Science Database, Directory of Open Access Journals
Page Numbers: pp.935-942
Keywords: Autophagy, Caspase-3, Detorsion, NF-kappa B, Ovarian, Torsion, Urapidil, ISCHEMIA-REPERFUSION INJURY, ISCHEMIA/REPERFUSION INJURY, TESTICULAR TORSION, RENAL ISCHEMIA, INHIBITION, ACID, MANAGEMENT, NECROSIS, PROTECTS, DAMAGE
Yozgat Bozok University Affiliated: Yes

Abstract

Objective(s): This study aimed to determine anti-inflammatory, antioxidant, and antiapoptotic properties of urapidil (Ura) against ovarian torsion detorsion (T/D) injury in rats.