Urapidil alleviates ovarian torsion detorsion injury via regulating oxidative stress, apoptosis, autophagia, and inflammation


GÜLER M. C. , TANYELİ A., Erdogan D. G. , ERASLAN E. , ÇOMAKLI S., Polat E., ...More

IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, vol.24, no.7, pp.935-942, 2021 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 24 Issue: 7
  • Publication Date: 2021
  • Doi Number: 10.22038/ijbms.2021.57196.12736
  • Title of Journal : IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES
  • Page Numbers: pp.935-942
  • Keywords: Autophagy, Caspase-3, Detorsion, NF-kappa B, Ovarian, Torsion, Urapidil, ISCHEMIA-REPERFUSION INJURY, ISCHEMIA/REPERFUSION INJURY, TESTICULAR TORSION, RENAL ISCHEMIA, INHIBITION, ACID, MANAGEMENT, NECROSIS, PROTECTS, DAMAGE

Abstract

Objective(s): This study aimed to determine anti-inflammatory, antioxidant, and antiapoptotic properties of urapidil (Ura) against ovarian torsion detorsion (T/D) injury in rats.