Urapidil alleviates ovarian torsion detorsion injury via regulating oxidative stress, apoptosis, autophagia, and inflammation

GÜLER, Mustafa; TANYELİ, Ayhan; Erdogan, Derya; ERASLAN, ERSEN; ÇOMAKLI, Selim; Polat, Elif; DOĞANAY, SONGÜL

doi:10.22038/ijbms.2021.57196.12736

Urapidil alleviates ovarian torsion detorsion injury via regulating oxidative stress, apoptosis, autophagia, and inflammation

GÜLER M. C., TANYELİ A., Erdogan D. G., ERASLAN E., ÇOMAKLI S., Polat E., ...More

IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, vol.24, no.7, pp.935-942, 2021 (SCI-Expanded, Scopus)

Publication Type: Article / Article
Volume: 24 Issue: 7
Publication Date: 2021
Doi Number: 10.22038/ijbms.2021.57196.12736
Journal Name: IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, CAB Abstracts, EMBASE, Index Islamicus, Veterinary Science Database, Directory of Open Access Journals
Page Numbers: pp.935-942
Keywords: Autophagy, Caspase-3, Detorsion, NF-kappa B, Ovarian, Torsion, Urapidil, ISCHEMIA-REPERFUSION INJURY, ISCHEMIA/REPERFUSION INJURY, TESTICULAR TORSION, RENAL ISCHEMIA, INHIBITION, ACID, MANAGEMENT, NECROSIS, PROTECTS, DAMAGE
Yozgat Bozok University Affiliated: Yes

Abstract

Objective(s): This study aimed to determine anti-inflammatory, antioxidant, and antiapoptotic properties of urapidil (Ura) against ovarian torsion detorsion (T/D) injury in rats.