Urapidil alleviates ovarian torsion detorsion injury via regulating oxidative stress, apoptosis, autophagia, and inflammation


GÜLER M. C., TANYELİ A., Erdogan D. G., ERASLAN E., ÇOMAKLI S., Polat E., ...More

IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, vol.24, no.7, pp.935-942, 2021 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 24 Issue: 7
  • Publication Date: 2021
  • Doi Number: 10.22038/ijbms.2021.57196.12736
  • Journal Name: IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, CAB Abstracts, EMBASE, Index Islamicus, Veterinary Science Database, Directory of Open Access Journals
  • Page Numbers: pp.935-942
  • Keywords: Autophagy, Caspase-3, Detorsion, NF-kappa B, Ovarian, Torsion, Urapidil, ISCHEMIA-REPERFUSION INJURY, ISCHEMIA/REPERFUSION INJURY, TESTICULAR TORSION, RENAL ISCHEMIA, INHIBITION, ACID, MANAGEMENT, NECROSIS, PROTECTS, DAMAGE
  • Yozgat Bozok University Affiliated: Yes

Abstract

Objective(s): This study aimed to determine anti-inflammatory, antioxidant, and antiapoptotic properties of urapidil (Ura) against ovarian torsion detorsion (T/D) injury in rats.