The Mediating Effect of Distrust of the Health System on the Relationship Between Health Literacy and Anti-Vaccination


Özdemir Ş., ŞANTAŞ F.

Journal of Evaluation in Clinical Practice, cilt.31, sa.4, 2025 (SCI-Expanded, Scopus) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 31 Sayı: 4
  • Basım Tarihi: 2025
  • Doi Numarası: 10.1111/jep.70140
  • Dergi Adı: Journal of Evaluation in Clinical Practice
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, CINAHL, MEDLINE, Psycinfo
  • Anahtar Kelimeler: anti-vaccination, distrust of the healthcare system, health literacy, mediating effect, patient
  • Yozgat Bozok Üniversitesi Adresli: Evet

Özet

Aim: This study aims to determine whether distrust of the health system has a mediating role in the effect of health literacy on anti-vaccination. Methods: The universe of the study consists of people over the age of 18 who apply to the polyclinics of Yozgat Akdağmadeni Şehit Sinan Babacan Public Hospital in Turkey and the number of people reached in this study was 450. Findings: According to the Process Macro analysis result, the total effect of health literacy on anti-vaccination (c = −0.115, p < 0.01) and its direct effect (c' = −0.073, p < 0.01) were negative and statistically significant. It was determined that health literacy negatively and significantly affected distrust of the health system (a = −0.098, p < 0.01) and distrust of the health system positively and significantly affected anti-vaccination (b = 0.432, p < 0.01). It was determined that distrust of the health system mediated the effect of health literacy on anti-vaccination in a statistically significant way [= −0.042 95% CI (−0.076; −0.012)]. Similar results were found in the structural equation modeling, but higher standardized and unstandardized loads and explained variance were obtained according to the Process Macro analysis result. Conclusion: According to the research results, individuals' distrust of the health system and their anti-vaccination can be reduced by increasing their health literacy.