A facile protocol for the preparation of 5-alkylidene and 5-imino substituted hydantoins from N,N '-disubstituted parabanic acids
TETRAHEDRON LETTERS, cilt.53, sa.35, ss.4758-4762, 2012 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 53 Sayı: 35
- Basım Tarihi: 2012
- Doi Numarası: 10.1016/j.tetlet.2012.06.129
- Dergi Adı: TETRAHEDRON LETTERS
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.4758-4762
- Anahtar Kelimeler: Wittig reactions, Hydantoins, Imidazolidine, Parabanic acid derivatives, Iminophosphoranes, DERIVATIVES, NITROGEN, UREAS
- Yozgat Bozok Üniversitesi Adresli: Evet
Özet
A convenient procedure for the preparation of various substituted (thio)hydantoins is described. The method is based on Wittig and aza-Wittig reactions of parabanic acids with phosphonium ylides. The reactions occurred both regio- and stereo-selectively. (c) 2012 Elsevier Ltd. All rights reserved.