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Education Information
2013 - 2016
2013 - 2016Postgraduate
Akdeniz University, Institute Of Health Sciences , Histoloji-Embriyoloji (Yl) (Tezli), Turkey
2011 - 2014
2011 - 2014Postgraduate
Hacettepe University, Fen Bilimleri Enstitüsü, Zooloji (Yl) (Tezli), Turkey
2004 - 2009
2004 - 2009Undergraduate
Hacettepe University, Fen Fakültesi, Biyoloji Bölümü, Turkey
Dissertations
2021
2021Doctorate
Linagliptinin insülin ile kombine tedavisinin tip 1 diyabetik fare ovaryumundaki katlanmamış protein cevabına olan etkisinin değerlendirilmesi
Akdeniz University, Faculty Of Medicine, Department Of Basic Medical Sciences
2015
2015Postgraduate
Stz-indüklenmiş diyabetik fare ovaryumunda endoplazmik retikulum stresi (ERS) ilişkili protein ekspresyonlarının değerlendirilmesi
Akdeniz University, Sağlık Bilimleri Enstitüsü, Histoloji-Embriyoloji (Yl) (Tezli)
2014
2014Postgraduate
Mirisetinin peripubertal dönemdeki erkek sıçanlarda tiroid gonadal eksen üzerine etkilerinin araştırılması
Hacettepe University, Fen Bilimleri Enstitüsü, Zooloji (Yl) (Tezli)
Foreign Languages
B1 Intermediate
B1 IntermediateEnglish
Research Areas
Health Sciences
Natural Sciences
Academic Titles / Tasks
2022 - Continues
2022 - ContinuesAssistant Professor
Yozgat Bozok University, Faculty of Medicine, Temel Tıp Bilimleri
2017 - 2022
2017 - 2022Research Assistant
Yozgat Bozok University, Faculty of Medicine, Temel Tıp Bilimleri
Published journal articles indexed by SCI, SSCI, and AHCI
2024
2024Investigation of the effects of melatonin on lung tissue through the NLRP3/TLR2/NEK7 pathway in an experimental endotoxemia model
TOKAT A. O., ÖZTÜRK O., OKAN OFLAMAZ A., UÇAR S., Eroğlu E., Doğanyi Ği Z., et al.
Cellular and molecular biology (Noisy-le-Grand, France)
, vol.70, no.10, pp.64-71, 2024 (SCI-Expanded)
2024
2024Evaluation of the effect of tartrazine on the offspring rats in an in vivo experimental model
ÖZTÜRK O., Dikici Y., Gür Ö., OCAK M., DOĞANYİĞİT Z., OKAN OFLAMAZ A., et al.
Food Science and Nutrition
, vol.12, no.11, pp.9162-9174, 2024 (SCI-Expanded)
2024
2024Histopathological, Antioxidant, and Enzyme Activity of Boronic Incorporated Catechin Compound: Screening of Bioactivity with Molecular Docking Studies
Paşa S., Atlan M., TEMEL H., TÜRKMENOĞLU B., Ertaş A., OKAN OFLAMAZ A., et al.
Russian Journal of Bioorganic Chemistry
, vol.50, no.4, pp.1446-1465, 2024 (SCI-Expanded)
2024
2024Effects of short- and long-term use of propolis extracts on liver and kidney in rats
SİLİCİ S., Demiray S., OKAN OFLAMAZ A., Ertuğrul S., Alizada S., DOĞANYİĞİT Z.
Food Science and Nutrition
, vol.12, no.8, pp.5538-5547, 2024 (SCI-Expanded)
2024
2024Protective role of olive oil extract of propolis on short and long-term administration of tamoxifen in rats
SİLİCİ S., KAYNAR L., OKAN OFLAMAZ A., DOĞANYİĞİT Z.
Environmental Toxicology
, vol.39, no.4, pp.2102-2122, 2024 (SCI-Expanded)
2024
2024Gender-related variation expressions of neuroplastin TRAF6, GluA1, GABA(A) receptor, and PMCA in cortex, hippocampus, and brainstem in an experimental epilepsy model
DOĞANYİĞİT Z., OKAN OFLAMAZ A., YILMAZ S., Uğuz A. C., Akyüz E.
Synapse
, vol.78, no.2, 2024 (SCI-Expanded)
2024
2024Linagliptin in combination with insulin suppresses apoptotic unfolded protein response in ovaries exposed to type 1 diabetes
OKAN OFLAMAZ A., Demir N., DOĞANYİĞİT Z.
Cell Biochemistry and Function
, vol.42, no.2, 2024 (SCI-Expanded)
2024
2024Evaluation of the anticarcinogenic effects of Rutin on brain tissue in mice with Ehrlich ascites carcinoma by micro-computed tomography and histological methods
OCAK M., ATEŞ Ş., KAHVECİ S., OKAN OFLAMAZ A., DOĞANYİĞİT Z., UÇAR S., et al.
Asia-Pacific Journal of Clinical Oncology
, 2024 (SCI-Expanded)
2024
2024Traumatic brain injury-induced peripheral damage: The dynamics of the inflammatory and autophagy pathway from acute to chronic stages
DOĞANYİĞİT Z., TAHERİ S., OKAN OFLAMAZ A., Yılmaz Z., Üner A. K., Akyüz E., et al.
Folia Neuropathologica
, vol.62, no.3, pp.277-292, 2024 (SCI-Expanded)
2024
2024Evaluation of TRPM2 Channel-Mediated Autophagic Signaling Pathway in Hippocampus and Cortex Tissues of Rat Offspring Following Prenatal Exposure to Elevated Alcohol Levels
Uğuz A. C., OKAN OFLAMAZ A., DOĞANYİĞİT Z., YILMAZ S., ATEŞ Ş., Arikan Söylemez E. S., et al.
Environmental Toxicology
, 2024 (SCI-Expanded)
2023
2023Can endoplasmic reticulum stress observed in the PTZ-kindling model seizures be prevented with TUDCA and 4-PBA?
DOĞANYİĞİT Z., OKAN OFLAMAZ A., Akyüz E., YILMAZ S., ATEŞ Ş., TAHERİ S., et al.
European Journal of Pharmacology
, vol.960, 2023 (SCI-Expanded)
2023
2023Evaluation of linagliptin and insulin combined therapy on unfolded protein response in type 1 diabetic mouse heart
Doğanyiğit Z., Okan A., Taheri S., Yılmaz Z., Akyüz E., Demir N.
Chemical Biology and Drug Design
, vol.102, no.5, pp.1085-1096, 2023 (SCI-Expanded)
2023
2023Intermediate filament proteins are reliable immunohistological biomarkers to help diagnose multiple tissue-specific diseases
Doğanyiğit Z., Eroglu E., Okan A.
Journal of Veterinary Medicine Series C: Anatomia Histologia Embryologia
, vol.52, no.5, pp.655-672, 2023 (SCI-Expanded)
2023
2023Is Testicular Tissue Resection Effective in Testicular Compartment Syndrome?
Caniklioğlu M., Oztekin Ü., Fırat F., Ataç F., Doğanyiğit Z., Oflamaz A.
Nigerian Journal of Clinical Practice
, vol.26, no.9, pp.1361-1367, 2023 (SCI-Expanded)
2023
2023Heterozygous Cc2d1a mice show sex-dependent changes in the Beclin-1/p62 ratio with impaired prefrontal cortex and hippocampal autophagy
ŞENER E. F., Dana H., Tahtasakal R., HAMURCU Z., TAHERİ S., Delibasi N., et al.
Progress in Neuro-Psychopharmacology and Biological Psychiatry
, vol.125, 2023 (SCI-Expanded)
2023
2023Immunoreactivity of Kir3.1, muscarinic receptors 2 and 3 on the brainstem, vagus nerve and heart tissue under experimental demyelination
Akyuz E., DOĞANYİĞİT Z., Okan A., YILMAZ S., UÇAR S., Akın A. T.
Brain Research Bulletin
, vol.197, pp.13-30, 2023 (SCI-Expanded)
2023
2023Evaluation of the protective role of resveratrol against sepsis caused by LPS via TLR4/NF-κB/TNF-α signaling pathways: Experimental study
Okan A., DOĞANYİĞİT Z., YILMAZ S., UÇAR S., Arikan Söylemez E. S., Attar R.
Cell Biochemistry and Function
, vol.41, no.4, pp.423-433, 2023 (SCI-Expanded)
2023
2023Determination of Rutin's antitumoral effect on EAC solid tumor by AgNOR count and PI3K/AKT/mTOR signaling pathway
Yılmaz S., Doğanyiğit Z., Oflamaz A., Ateş Ş., Söylemez E. S. A., Nisari M., et al.
Medical Oncology
, vol.40, no.5, 2023 (SCI-Expanded)
2023
2023Tauroursodeoxycholic Acid (TUDCA) Regulates Inflammation and Hypoxia in Autonomic Tissues of Rats with Seizures
Üner A. K., Okan A., Akyüz E., Köklü B., Eroğlu E., YILMAZ S., et al.
Cellular and molecular biology (Noisy-le-Grand, France)
, vol.68, no.12, pp.104-111, 2023 (SCI-Expanded)
2023
2023Detection of melatonin protective effects in sepsis via argyrophilic nucleolar regulatory region-associated protein synthesis and TLR4/NF-κB signaling pathway.
Yılmaz S., Doğanyiğit Z., Oflamaz A., Ateş Ş., Uçar S., Söylemez E. S. A.
Chemical biology & drug design
, vol.101, no.4, pp.915-926, 2023 (SCI-Expanded)
2023
2023The increase in c-fos expression in epileptic seizures is inhibited by magnetic field application, but not KCa1.1 channel expression
Akdağ M. Z., Oğraş E., DOĞANYİĞİT Z., Akyüz E., Akdag M. B., Okan A., et al.
Electromagnetic Biology and Medicine
, vol.42, no.2, pp.81-97, 2023 (SCI-Expanded)
2022
2022Cream production and biological in vivo/in vitro activity assessment of a novel boron-based compound derived from quercetin and phenyl boronic acid
Temel H., Atlan M., Ertaş A., Yener I., Akdeniz M., Yazan Z., et al.
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
, vol.74, 2022 (SCI-Expanded)
2022
2022Receptivity, autophagy, and implantation in endometriosis; does antioxidant work? An experimental study
AYDOĞAN KIRMIZI D., BAŞER E., OKAN OFLAMAZ A., DOĞANYİĞİT Z.
JOURNAL OF FOOD BIOCHEMISTRY
, vol.46, no.10, 2022 (SCI-Expanded)
2022
2022Toxicity of Propylene Glycol Extract of Propolis on Central Nervous System and Liver in Pregnant and Neonatal Rats
SİLİCİ S., Okan A., Köklü B., Demiray S., DOĞANYİĞİT Z.
Zeitschrift fur Geburtshilfe und Neonatologie
, vol.227, no.4, pp.261-268, 2022 (SCI-Expanded)
2021
2021Immunoreactive definition of TNF- alpha, HIF-1 alpha, Kir6.2, Kir3.1 and M2 muscarinic receptor for cardiac and pancreatic tissues in a mouse model for type 1 diabetes
Okan A., Doğanyiğit Z., Eroğlu E., Akyüz E., Demir N.
LIFE SCIENCES
, vol.284, 2021 (SCI-Expanded)
2021
2021Nephroprotective effect of apilarnil in lipopolysaccharide-induced sepsis through TLR4/NF-κB signaling pathway.
İnandıklıoğlu N., Doğanyiğit Z., Okan A., Kaymak E., Silici S.
Life sciences
, vol.284, pp.119875, 2021 (SCI-Expanded)
2021
2021Unfolded protein response triggers differential apoptotic mechanisms in ovaries and early embryos exposed to maternal type 1 diabetes
Okan A., DEMİR N., Sozen B.
SCIENTIFIC REPORTS
, vol.11, no.1, 2021 (SCI-Expanded)
2021
2021The effect of a natural molecule in ovary ischemia reperfusion damage: does lycopene protect ovary?
Aydoğan Kırmızı D., Başer E., Okan Oflamaz A., Kara M., Yalvaç E. S., Doğanyiğit Z.
EXPERIMENTAL ANIMALS
, vol.70, no.1, pp.37-44, 2021 (SCI-Expanded)
2020
2020Investigation of protective effects of apilarnil against lipopolysaccharide induced liver injury in rats via TLR 4/ HMGB-1/ NF-kappa B pathway
DOĞANYİĞİT Z., OKAN OFLAMAZ A., KAYMAK E., PANDIR D., SİLİCİ S.
BIOMEDICINE & PHARMACOTHERAPY
, vol.125, 2020 (SCI-Expanded)
2020
2020Histological, immunohistochemical and biochemical effects of bee bread on stomach tissue of obese rats
Doganyigit Z., Yakan B., Soylu M., Kaymak E., Okan A., Silici S.
BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY
, vol.121, no.7, pp.504-511, 2020 (SCI-Expanded)
2020
2020The ameliorating effect of cannabinoid type 2 receptor activation on brain, lung, liver and heart damage in cecal ligation and puncture-induced sepsis model in rats
Çakır M., Tekin S., Okan Oflamaz A., Cakan P., Doğanyiğit Z.
INTERNATIONAL IMMUNOPHARMACOLOGY
, vol.78, 2020 (SCI-Expanded)
2019
2019Cannabinoid Type 2 Receptor Activation Reduces Inflammation and Apoptosis in the Lung in Model of Sepsis Induced by Cecal Ligation Puncture
ÇAKIR M., TEKİN S., DOĞANYİĞİT Z., OKAN OFLAMAZ A.
ACTA PHYSIOLOGICA
, vol.227, pp.59, 2019 (SCI-Expanded)
2015
2015Investigation of effects of myricetin on thyroid-gonadal axis of male rats at prepubertal period
OKAN OFLAMAZ A., BARLAS N., Karabulut G.
ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY
, vol.40, no.1, pp.268-279, 2015 (SCI-Expanded)
Articles Published in Other Journals
2024
2024Evaluation of the Anticarcinogenic Effect of White Radish Extract (Raphanus sativus var. Longipinnatus) on In Vitro Ehrlich Ascites Tumor Cells
UÇAR S., OFLAMAZ A. O., OCAK M.
Gümüşhane Üniversitesi Sağlık Bilimleri Dergisi
, vol.13, no.3, pp.1003-1008, 2024 (Peer-Reviewed Journal)
2024
2024PI3K AND MTOR IMMUNOREACTIVITY IN TESTICULAR TISSUE IN EXPERIMENTAL ALCOHOL ADDICTION MODEL
ÖZTÜRK O., OKAN A., KURT M., EROĞLU E., YILMAZ S., UĞUZ A. C., et al.
Gümüşhane Üniversitesi Sağlık Bilimleri Dergisi
, vol.13, no.3, pp.1119-1124, 2024 (Peer-Reviewed Journal)
2024
2024Effect of copper sulphate in rat brain tissue: Kir channels
KAHVECİ S., ÖZTÜRK O., UÇAR S., OKAN OFLAMAZ A., GÖKMEN D., YILMAZ S., et al.
TURK HIJIYEN VE DENEYSEL BIYOLOJI DERGISI. TURKISH BULLETIN OF HYGIENE AND EXPERIMENTAL BIOLOGY , vol.81, 2024 (Scopus)
2023
2023Tartrazinin Rat Plasentası Üzerine Etkisi
ÖZTÜRK O., KAHVECİ S., OKAN OFLAMAZ A., UÇAR S., YILMAZ S., DOĞANYİĞİT Z.
Bozok Tıp Dergisi , vol.13, no.4, pp.123-130, 2023 (Peer-Reviewed Journal)
2023
2023Immunoreactivity of NOS2 and NF-κB in Kidney Tissue in Experimental Alcohol Consumption Model
OKAN A., Uguz A. C., ÖZTÜRK O., EROGLU E., YILMAZ S., DOĞANYİĞİT Z.
Ankara Üniversitesi Tıp Fakültesi Mecmuası
, vol.76, no.1, pp.17-23, 2023 (Peer-Reviewed Journal)
2023
2023Can 900 MHz and 2100 MHz radiofrequency radiation exposure induce endoplasmic reticulum stress and apoptosis in rat thymus?
Kaya E., Kirimlioglu E., ER H., OKAN A., ÖZEN Ş., Demir N.
The European Research Journal
, vol.9, no.1, pp.29-38, 2023 (Peer-Reviewed Journal)
2023
2023IMMUNOHISTOCHEMICAL NEUROINFLAMMATORY MARKERS IN THE HIPPOCAMPUS OF PTZ-KINDLED RATS UNDER CONDITIONS OF RAPAMYCIN AND AXITINIB TREATMENT
Poshyvak O., Pinyazhko O., Godlevsky L., Pervak M., Yehorenko O., DOĞANYİĞİT Z., et al.
ScienceRise: Pharmaceutical Science
, vol.41, no.1, pp.23-31, 2023 (Scopus)
2022
2022Apilarnil protects the LPS induced endotoxemic heart
OKAN OFLAMAZ A., KAYMAK E., ÜNER A. K., SİLİCİ S., DOĞANYİĞİT Z.
TURK HIJIYEN VE DENEYSEL BIYOLOJI DERGISI. TURKISH BULLETIN OF HYGIENE AND EXPERIMENTAL BIOLOGY
, vol.79, no.4, pp.720-729, 2022 (Scopus)
2022
2022Histological, Hematological and Biochemical Effects of Bee Bread on DSS-Induced Colitis Model in Rats
SİLİCİ S., ÖZER S., OKAN OFLAMAZ A., AYCI B., SOYLU M., DOĞANYİĞİT Z.
ECronicon Pharmacology and Toxicology , pp.43-52, 2022 (Peer-Reviewed Journal)
2022
2022Increased Immunohistochemical Expression of mGluR5 in Brainstem, Vagus Nerve and Heart in PTZ-Kindled Rats
ÜNER A. K., OKAN OFLAMAZ A., AKYÜZ E., DOĞANYİĞİT Z.
Journal of US-China Medical Science , vol.19, no.2022, pp.20-27, 2022 (Peer-Reviewed Journal)
2022
2022ON THE ROLE OF ATP-DEPENDENT POTASSIUM CHANNEL Kir6.2 AND HYPOXIA-INDUCED FACTOR-1α IN THE PENTYLENETETRAZOLE KINDLING PATHOGENESIS
DOĞANYİĞİT Z., OKAN OFLAMAZ A., AKYÜZ E., Poshyvak O., Pervak M., Yehorenko O., et al.
WORLD OF MEDICINE AND BIOLOGY , vol.18, 2022 (Peer-Reviewed Journal)
2022
2022ON THE ROLE OF TUMOR NECROSIS FACTOR-ALPHA (TNF-α) AND NUCLEAR FACTOR p-NF-κB IN THE PENTYLENETETRAZOLE KINDLING PATHOGENESIS
DOĞANYİĞİT Z., OKAN OFLAMAZ A., AKYÜZ E., POSHYVAK O. B., PERVAK M., YEHORENKO O., et al.
Odessa National Medical University
, vol.2022, pp.15-20, 2022 (Scopus)
2021
2021Inflammation-Associated HMGB1, α7nAChR, Kir6.2 and Beclin1 Immunoreactivity in PTZ-Kindled Model Seizures in Rats
Köklü B., POLAT A. K., EROĞLU E., Küllü İ., OKAN OFLAMAZ A., DOĞANYİĞİT Z., et al.
Journal of US-China Medical Science
, vol.18, no.2021, pp.57-75, 2021 (Peer-Reviewed Journal)
2021
2021Protective effect of propolis and bee bread in experimental gastric ulser model.
DOĞANYİĞİT Z., ÜNER A. K., OKAN OFLAMAZ A., SİLİCİ S.
Mellifera , vol.21, no.1, pp.18-28, 2021 (Peer-Reviewed Journal)
2021
2021Protective Effect of Propolis and Bee Bread in Experimental Gastric Ulcer Model
DOĞANYİĞİT Z., ÜNER A. K., OKAN OFLAMAZ A., SİLİCİ S.
Mellifera , vol.21, no.1, pp.18-28, 2021 (Peer-Reviewed Journal)
2021
2021The Antitumor Effect of Rhamnetin on the Heart
YILMAZ S., DOĞANYİĞİT Z., TOKPINAR A., BOZKURT Ö., OKAN OFLAMAZ A., Kurt Tokpınar R., et al.
Journal of US-China Medical Science , vol.18, no.3, pp.122-127, 2021 (Peer-Reviewed Journal)
2020
2020The Effect of Apilarnil on the Autophagia Against Lipolysaccarite-BasedSepsis in Liver
DOĞANYİĞİT Z., Köklü B., Üner A., OKAN A., KAYMAK E., SİLİCİ S.
New Trend Med Sci , 2020 (Peer-Reviewed Journal)
2020
2020Lipopolisakkarit’in neden olduğu bağırsak toksisitesine karşıbiyosentetik gümüş nanopartiküllerin etkisi
ÖZTÜRK KÜP F., Koçak B., AKİN A. T., Doğanyiğit İ., OKAN A., KAYMAK E., et al.
Türk Hijyen ve Deneysel Biyoloji Dergisi , 2020 (Scopus)
2020
2020Antioxidative role of propolis on LPS induced renal damage
DOĞANYİĞİT Z., YAKAN B., OKAN OFLAMAZ A., SİLİCİ S.
EUROBIOTECH JOURNAL
, vol.4, no.3, pp.156-160, 2020 (ESCI)
2020
2020Apilarnil: A Novel Neuroprotective Candidate
HAMAMCI M., DOĞANYİĞİT Z., SİLİCİ S., OKAN A., KAYMAK E., YILMAZ S., et al.
Acta Neurologica Taiwanica
, vol.29, no.2, pp.33-45, 2020 (Scopus)
2020
2020Investigation of Protective Effects of Apilarnil Against Lipopolysaccharide Induced Lung Injury in Rats
DOĞANYİĞİT Z., KAYMAK E., OKAN A., PANDIR D., SİLİCİ S.
MELLIFERA , vol.20, no.1, pp.3-15, 2020 (Peer-Reviewed Journal)
2019
2019LPS’nin böbrek DNA’sı üzerine akut toksik etkisi ve apilarnilin koruyucu rolü
DOĞANYİĞİT Z., SİLİCİ S., KAYMAK E., OKAN A., PANDIR D.
Eurasian Journal of Biological and Chemical Sciences , vol.2, pp.111-114, 2019 (Peer-Reviewed Journal)
2019
2019The Influence of the Myricetin on the Liver, Kidney, Spleen and Some Endocrine Glands of Male Rats at Prepubertal Period
BARLAS N., OKAN A.
Hacettepe Journal of Biology and Chemistry
, vol.47, no.3, pp.317-326, 2019 (Peer-Reviewed Journal)
2019
2019GÜMÜŞ NANOPARTİKÜLLERİNİN ÜZÜM ÇEKİRDEĞİ EKSTRAKTININ ENDOTOKSİK KALP DOKUSUNDAKİ HİSTOLOJİK DEĞİŞİKLERE VE TNF-ɑ VE BNP EKSPRESYONUNA ETKİSİ
DOĞANYİĞİT Z., ÖZTÜRK KÜP F., KAYMAK E., OKAN A., Koçak B., AKİN A. T.
Bozok Tıp Dergisi , vol.9, no.3, pp.87-96, 2019 (Peer-Reviewed Journal)
2019
2019APİLARNİLİN ERKEK SIÇANLARDA LİPOPOLİSAKKARİTE (LPS) BAĞLI TESTİS TOKSİSİTESİNE KARŞI KORUYUCU ROLÜNÜN BELİRLENMESİ
DOĞANYİĞİT Z., SİLİCİ S., KAYMAK E., OKAN A., AKİN A. T., PANDIR D.
Bozok Tıp Dergisi , vol.9, no.2, pp.146-154, 2019 (Peer-Reviewed Journal)
2018
2018Nörodejeneratif Hastalıklarda Katlanmamış Protein Cevabının Tedavi Edici Potansiyeli
OKAN A., DEMİR N.
Akdeniz Medical Journal
, vol.2, pp.104-113, 2018 (Peer-Reviewed Journal)
Refereed Congress / Symposium Publications in Proceedings
2024
2024DENEYSEL DİYABET MODELİNDE PANKREASTA S100 İFADESİ
Erdağ D., BOR T. B., OKAN OFLAMAZ A.
1. ULUSAL SAĞLIK BİLİMLERİ ÖĞRENCİ KONGRESİ & UNIKOP II. ÖĞRENCİ KALİTE BULUŞMASI, 5-6 HAZİRAN 2024, Kırıkkale, Turkey, 05 June 2024, vol.1, pp.1-319
2024
2024DENEYSEL TİP 1 DİYABETLİ KARACİĞER DOKUSUNDA BECLİN-1 PROTEİNİNİN İMMÜNOHİSTOKİMYASAL OLARAK GÖSTERİLMESİ
AĞCA R. A. B., BOR T. B., OKAN OFLAMAZ A.
1. ULUSAL SAĞLIK BİLİMLERİ ÖĞRENCİ KONGRESİ & UNIKOP II. ÖĞRENCİ KALİTE BULUŞMASI, 5-6 HAZİRAN 2024, Kırıkkale, Turkey, 05 June 2024, vol.1, pp.1-319
2023
2023Investigation of the Effects of Melatonin on Brain Tissue in EAC Tumor Model by Immunostaining Via TNF-α, NF-κB, IL-6
KAHVECİ S., YILMAZ S., UÇAR S., OKAN OFLAMAZ A., ATEŞ Ş., DOĞANYİĞİT Z.
4th INTERNATIONAL CANCER DAYS, Sivas, Turkey, 28 August - 30 September 2023
2023
2023Maternally alcohol exposure increased NFk-β, Tnf-α, TLR4 and TRPM2 expression levels in liver tissue of offspring rats
UĞUZ A. C., OKAN OFLAMAZ A., KAHVECİ S., YILMAZ S., Uğuz A., DOĞANYİĞİT Z., et al.
12th Swiss Apoptosis and Autophagy Meeting 2023, Bern, Switzerland, 07 September 2023
2023
2023INVESTIGATION OF TRPM2 CHANNEL-MEDIATED AUTOPHAGIC SIGNALING PATHWAY IN HIPPOCAMPUS AND CORTEX TISSUES IN OFFSPRING EXPOSED TO MATERNAL HIGH-DOSE ALCOHOL
UĞUZ A. C., OKAN OFLAMAZ A., DOĞANYİĞİT Z., YILMAZ S., ATEŞ Ş., ARIKAN SÖYLEMEZ E. S., et al.
11th IBRO World Congress of Neuroscience, Granada, Nicaragua, 09 September 2023, vol.15, pp.146
2023
2023INVESTIGATION OF THE EFFECTS OF MELATONIN ON BRAIN TISSUE IN EAC TUMOUR MODEL BY IMMUNOSTAINING VIA TNF-a, NF-kB, IL-6
KAHVECİ S., YILMAZ S., UÇAR S., OKAN OFLAMAZ A., ATEŞ Ş., DOĞANYİĞİT Z.
4TH INTERNATIONAL CANCER DAYS, Sivas, Turkey, 28 - 30 September 2023
2023
2023INVESTIGATION OF THE EFFECTS OF MELATONIN ON BRAIN TISSUE IN EAC TUMOUR MODEL BY IMMUNOSTAINING VIA TNF-, NF-kB, IL-6
KAHVECİ S., YILMAZ S., UÇAR S., OKAN OFLAMAZ A., ATEŞ Ş., DOĞANYİĞİT Z.
The 4th International Cancer Days (4th ICD 2023), Sivas, Turkey, 28 - 30 September 2023
2023
2023Tartrazinin Rat Plasentası Üzerine Etkisi
KAHVECİ S., ÖZTÜRK O., OKAN OFLAMAZ A., YILMAZ S., DOĞANYİĞİT Z.
26. Ulusal Elektron Mikroskoppi Kongresi, Eskişehir, Turkey, 20 - 23 September 2023
2023
2023Maternally alcohol exposure increased NF-kB, Tnf-a, TLR4 and TRPM2 expression levels in liver tissue of offspring rats
UĞUZ A. C., OKAN OFLAMAZ A., KAHVECİ S., YILMAZ S., UĞUZ A., DOĞANYİĞİT Z.
Swiss Apoptosis & Autophagy Meeting (SA2M) 2023, Switzerland, 07 September 2023
2023
2023DENEYSEL EPİLEPSİ MODELİNDE BEYİN SAPI VE HİPOKAMPÜSTE İNTEGRİN İFADESİ INTEGRIN EXPRESSION IN THE BRAINSTEM AND HIPPOCAMPUS IN AN EXPERIMENTAL MODEL OF EPILEPSY
Erdağ D., OKAN OFLAMAZ A., DOĞANYİĞİT Z.
9. ULUSLARARASI ERCİYES BİLİMSEL ARAŞTIRMALAR KONGRESİ, Kayseri, Turkey, 17 July 2023
2023
2023Pentilentetrazol Tutuşma Epilepsi Modelinde Beyin Sapı, Akciğer ve Kalp Dokusunda MyD88 İmmünreaktivitesi
Küllü İ., OKAN OFLAMAZ A., DOĞANYİĞİT Z.
21. Ulusal Sinirbilim Kongresi, 8-11 Haziran 2023 Bolu Abant İzzet Baysal Üniversitesi, Bolu, Turkey, 08 June 2023
2023
2023DENEYSEL EPİLEPSİ MODELİNDE KORTEKS, HİPOKAMPUS VE BEYİN SAPINDA NÖROPLASTİN, TRAF6, GLUA1, GABA(A) RESEPTÖRÜ VE PMCA İFADELERİNEUROPLASTIN, TRAF6, GLUA1, GABA(A) RECEPTOR, AND PMCA EXPRESSIONS IN CORTEX, HIPPOCAMPUS, AND BRAIN STEM IN EXPERIMENTAL EPILEPSY MODEL
OKAN OFLAMAZ A., DOĞANYİĞİT Z., YILMAZ S.
ICHEAS 4TH INTERNATIONAL CONFERENCE ON HEALTH, ENGINEERING AND APPLIED SCIENCES APRIL 14 - 16, 2023 DUBAI, 14 - 16 April 2023
2022
2022TRPM2 channel mediated JNK/mTOR signaling pathway regulates autophagy in off springs’heart tissue of high döşe alcohol exposure during pregnancy: Impact of gender difference.
UĞUZ A. C., OKAN OFLAMAZ A., YILMAZ S., ARIKAN E. S., DOĞANYİĞİT Z.
XL Congress of the Spanish Society of Physiological Sciences, Badajoz, Spain, 19 September 2022
2022
2022Effect of Linagliptin and Insulin Combined Therapy on Unfolded Protein Response in Type 1 Diabetic Mouse Heart
DOĞANYİĞİT Z., OKAN OFLAMAZ A., DEMİR N., Üner A. K., TAHERİ S.
1st International Congress of Histology and Embryology, 26 May 2022
2022
2022TLR4 expression in the brainstem and heart tissue in experimental epilepsy model
Küllü İ., OKAN OFLAMAZ A., DOĞANYİĞİT Z.
2nd Hamidiye International Student Congress (HISCON 2022), May 10-11, 2022/online, Turkey, 10 May 2022
2022
2022Sıçanlarda Lipopolisakkarit (LPS) ile Oluşturulan Endotoksik Şok Üzerine Melatoninin Etkilerinin Histolojik, İmmünohistokimyasal ve Biyokimyasal Yönden Araştırılması
YILMAZ S., DOĞANYİĞİT Z., OKAN OFLAMAZ A., ATEŞ Ş.
X. ANATOMİ KIŞ GÜNLERİ, Hatay, Turkey, 17 March 2022
2021
2021Linagliptinin İnsülin İle birlikte kullanımı Tip 1 diyabetik fare ovaryumunda Pro- apoptotik Chop/Ddit3 mRNA ifadesini azaltır
OKAN OFLAMAZ A., DEMİR N.
25. ULUSAL ELEKTRON MİKROSKOPİ KONGRESİ, Turkey, 22 September 2021
2021
2021Determination of antitumoral effect of rhamnetin on EAC solid tumor by suppressing PI3K / AKT / mTOR signaling pathways
YILMAZ S., TOKPINAR A., ATEŞ Ş., OKAN OFLAMAZ A., DOĞANYİĞİT Z.
2. International Canser Day Congress, Sivas, Turkey, 16 - 18 September 2021
2021
2021Concomitant Use of Linagliptin and Insulin in a Mouse Model of Type 1 Diabetes is effective in Preserving Follicle Reserve
OKAN OFLAMAZ A., DEMİR N.
1st Hamidiye International Student Congress (HISCON2021),Online, Turkey, 23 July 2021
2021
2021Immunoreactive Definition of TNF𝜶, HIF-1𝜶, Kir6.2, Kir3.1 and M2 Muscarinic Receptor for Cardiac and Pancreatic Tissues in a mouse model for type 1 diabetes.
OKAN OFLAMAZ A., DOĞANYİĞİT Z., EROĞLU E., AKYÜZ E., DEMİR N.
1st Hamidiye International Student Congress (HISCON2021),online, Turkey, 23 July 2021, pp.50
2021
2021Does rhamnitin have an effect on P13K, AKT1 and mTOR signaling pathways in mice with Ehrlich Ascites Tumor (EAT)?
YILMAZ S., TOKPINAR A., DOĞANYİĞİT Z., OKAN OFLAMAZ A., UNUR E., NİSARİ M.
HISCON 2021, İstanbul, Turkey, 23 July 2021
2020
2020Cornus Mas L (Kızılcık) Bitkisinin Beyin Üzerine Anti-TümörEtkisi Var Mıdır?- Does Cornus Mas L Have Antı-TumorEffect On The Braın?
YILMAZ S., TOKPINAR A., ATEŞ Ş., OKAN A., DOĞANYİĞİT Z.
21. Ulusal Anatomi Kongresi, 28 - 29 November 2020
2020
2020Cornus Mas L (Kızılcık) Bitkisinin Beyin Üzerine Anti-TümörEtkisi Var Mıdır?
YILMAZ S., TOKPINAR A., ATEŞ Ş., OKAN OFLAMAZ A., DOĞANYİĞİT Z.
21. Ulusal Anatomi Kongresi, İstanbul, Turkey, 28 November 2020
2020
2020Sıçanlarda lipopolisakkaritle oluşturulan böbrek hasarına karşı apilarnilin koruyucu etkilerinin otofajik yönden değerlendirilmesi
OKAN A., KAYMAK E., DOĞANYİĞİT Z., SİLİCİ S.
3rd International Eurasian Conference on Biological and Chemical Sciences, Ankara, Turkey, 19 - 20 March 2020
2019
2019Cannabinoid Type 2 Receptor Activation Reduces Inflammation and Apoptosis in the Lung in Model of Sepsis Induced by Cecal Ligation Puncture
ÇAKIR M., TEKİN S., DOĞANYİĞİT Z., OKAN A.
Turkish Society of Physiological Sciences 45th National Physiology Congress, Aydın, Turkey, 31 October - 03 November 2019, vol.227
2019
2019Investigation of the effect of grape seed, silver nitrate and silver nanoparticle on kidney damage induced by lipopolysaccharide (LPS)
DOĞANYİĞİT Z., KAYMAK E., OKAN A., AKİN A. T., ÖZTÜRK KÜP F.
6th International Conference on Materials Science and Nanotechnology For Next Generation (MSNG2019), Niğde, Turkey, 16 - 18 October 2019
2019
2019Investigation of protective effects of apilarnil against lipopolysaccharide induced lung injury in rats
DOĞANYİĞİT Z., KAYMAK E., OKAN A., SİLİCİ S.
5th International Eurasian Congress on Natural Nutrition, Healthy Life Sport, Ankara, Turkey, 2 - 06 October 2019
2019
2019LPS’nin böbrek DNA’sı üzerine akut toksik etkisi ve apilarnilin koruyucu rolü
DOĞANYİĞİT Z., SİLİCİ S., KAYMAK E., OKAN A., PANDIR D.
2nd International Eurasian Conference on Biological and Chemical Sciences, Ankara, Turkey, 28 - 29 June 2019
2019
2019Cecal Ligation and Puncture-Induced Sepsis in Rats Causes Amyloid Beta Protein Accumulation and Tau Hyperphosphorylation in Brain Tissue
OKAN A., ÇAKIR M., DOĞANYİĞİT Z.
6th International Symposium on Academic Studies in Health and Sport Sciences, Ankara, Turkey, 13 - 15 June 2019
2019
2019Sıçanlarda Çekal Ligasyon ve Puncture ile Oluşturulan Sepsis, Beyin Dokusunda Amiloid Beta Protein Birikimi ve Tau Hiperfosforilizasyonuna Neden Olur
OKAN A., ÇAKIR M., DOĞANYİĞİT Z.
6th International Symposium on Academic Studies in Health and Sport Sciences, 13 - 15 June 2019
2018
2018Endoplazmik retikulum stresi ile iliskili katlanmamis protein cevabi hiperglisemik kosullar altinda fare ovaryumlarinda apoptozu tetikler
OKAN A., SÖZEN B., DEMİR N.
14. Ulusal Histoloji ve Embriyoloji Kongresi, Antalya, Turkey, 10 - 13 May 2018
2018
2018Gebeliğin 5. ve 8. Günlerinde AXL Reseptörünün Desidualizasyon ve Gebeliğin Devamındaki Rolünün Araştırılması
KONUK E., OKAN A., ORHAN E., KATIRCI E., Quliyeva F., DEMİR N.
14. Ulusal Histoloji ve Embriyoloji Kongresi, Antalya, Turkey, 10 - 13 May 2018
2018
20183G Cep Telefonlarından Yayılan Elektromanyetik Radyasyonun Testis Dokusunda Tam Reseptör Kinazların (TAMRTK) ve Ligandlarının Ekspresyonlarına Etkisinin Değerlendirilmesi
KATIRCI E., KONUK E., OKAN A., HİDİŞOĞLU E., YARGIÇOĞLU AKKİRAZ P., DEMİR N.
14. Ulusal Histoloji ve Embriyoloji Kongresi, Antalya, Turkey, 10 - 13 May 2018
2017
2017İmmunohistochemical evaluation of endoplasmic reticulum stress-related protein expressions in streptozocin-induced diabetic mouse ovary
OKAN A., SÖZEN B., DEMİR N.
15th International Congress of Histochemistry and Cytochemistry, 18 - 21 May 2017
2015
2015Antibakteriyel Sterione Gümüş İyonu İçeren Kaplamalı İmplantların Kemik Doku Uyumluluğu
KIRIMLIOĞLU E., OKAN OFLAMAZ A., DEMİR N.
22. Elektron Mikroskopi Kongresi (EMK2015), Turkey, 02 September 2015
2015
2015Hiperglisemik Koşulların Fare Blastosistlerindeki Endoplazmik Retikulum Stresine Etkisinin Araştırılması
Sözen B., OKAN OFLAMAZ A., DEMİR N.
22. Elektron Mikroskopi Kongresi, 02 September 2015
2015
2015Hiperglisemik Uterin Mikroçevrenin Blastosistlerdeki Endoplazmik Retikulum Stres Yanıtlarına Etkisi
OKAN A., SÖZEN B., DEMİR N.
V.Üreme Tıbbı ve Cerrahisi Derneği Kongresi, Turkey, 28 - 31 October 2015
2015
20153G Cep Telefonlarından Yayılan Elektromanyetik Radyasyonun Testis Seminifer Tübül Hücrelerinde Endoplazmik Retikulum Stres Yolağı Üzerine Etkisi
OKAN A., KONUK E., HİDİŞOĞLU E., YARGIÇOĞLU AKKİRAZ P., DEMİR N.
22.Elektron Mikroskopi Kongresi, İstanbul, Turkey, 2 - 04 September 2015
2014
2014İn Vitro Hiperglisemik Koşullara Maruz Kalan Fare Blastosistlerinde Endoplazmik Retikulum Stres Proteinlerinin Araştırılması
OKAN A., SÖZEN B., DEMİR N.
6.Ulusal Üreme Endokrinolojisi ve İnfertilite Kongresi, Antalya, Turkey, 6 - 09 November 2014
2014
2014Fare Ovaryumunda Endoplazmik Retikulum (ER) Stres Protein Ekspresyonlarının Araştırılması
OKAN OFLAMAZ A., Sözen B., DEMİR N.
12. Ulusal Histoloji ve Embriyoloji Kongresi, Ankara, Turkey, 27 May 2014
Books & Book Chapters
2023
2023Lavantanın Biyolojik Aktiviteleri
KAHVECİ S., OKAN OFLAMAZ A., DOĞANYİĞİT Z.
in: Sağlık Bilimleri Açısından Lavanta, TEMEL Hamdi, Editor, Antalya Nobel Kitabevi, pp.57-63, 2023
2022
2022Ovaryan Yaşlanmada Mitokondrinin Rolü
OKAN OFLAMAZ A.
in: Sağlık Bilimlerinde Araştırma ve Değerlendirmeler-I, Selamoğlu Zeliha, Akgül Hasan, Bahşi İlhan, Editor, Gece Kitaplığu, Ankara, pp.311-324, 2022
2022
2022ENDOPLAZMİK RETİKULUM VE KATLANMAMIŞ PROTEİN CEVABI
OKAN OFLAMAZ A., DEMİR N.
in: SAĞLIK BİLİMLERİNDE GÜNCEL ARAŞTIRMALAR-II, ŞAHNA Engin, AKGÜL Hasan, Editor, Gece Kitaplığı, Ankara, pp.439-449, 2022
2021
2021GLIAL MARKERS USED IN IMMUNOHISTOCHEMISTRY
DOĞANYİĞİT Z., OKAN OFLAMAZ A.
in: Research & Reviews in Health Sciences - I, PROF. DR. CEM EVEREKLİOĞLU, Editor, Gece Kitaplığı / Gece Publishing, Ankara, pp.1-14, 2021
2020
2020Liver Development, Liver Histology and The Role of The Liver in Sepsis
DOĞANYİĞİT Z., OKAN A.
in: Academic Studies in Health Sciences - IIVolume 2, Doç.Dr. Özgür SARI, Editor, Gece Kitaplığı / Gece Publishing, Ankara, pp.167-186, 2020
Supported Projects
2024 - Continues
2024 - ContinuesDeneysel Otizm Spektrum Bozukluğunda Otonomik Sistemin Asetilkolin Ilişkili Merkezler Üzerinden Histolojik Tayini
Project Supported by Higher Education Institutions
DOĞANYİĞİT Z. (Executive), YILMAZ S., OKAN OFLAMAZ A., AKYÜZ E., UÇAR S., HASSANZADEH FAALASLI M., et al.
2020 - Continues
2020 - ContinuesLinagliptin Ve İnsülin Kombine Tedavisinin Tip 1 Diyabetik Fare Kalbindeki Katlanmamış Protein Cevabına Olan Etkisinin Değerlendirilmesi
Project Supported by Higher Education Institutions
DOĞANYİĞİT Z. (Executive), OKAN OFLAMAZ A.
2024 - 2024
2024 - 2024Yavru Ratlarda Bakır Sülfatın Dokular Üzerine Etkilerinin Histolojik ve Moleküler Düzeyde Araştırılması
Project Supported by Higher Education Institutions
ÖZTÜRK O. (Executive), DOĞANYİĞİT Z., YILMAZ S., OKAN OFLAMAZ A., UÇAR S.
2023 - 2023
2023 - 2023Deneysel Endotoksemi Modelinde Akciğer Dokusu Üzerine Melatoninin Etkilerinin NLRP3TLR2NEK7 Yolağı Üzerinden Araştırılması
Project Supported by Higher Education Institutions
TOKAT A. O. (Executive), UÇAR S., DOĞANYİĞİT Z., YILMAZ S., OKAN OFLAMAZ A., ÖZTÜRK O.
2022 - 2023
2022 - 2023Deneysel Epilepsi Modelinde Korteks Hipokampus ve Beyin sapında Nöroplastin TRAF6 GluA1 GABAA reseptörü ve PMCA İfadeleri
Project Supported by Higher Education Institutions
DOĞANYİĞİT Z. (Executive), YILMAZ S., OKAN OFLAMAZ A.
2022 - 2023
2022 - 2023Deneysel Epilepsi Modelinde Solunum İzlemi ve Akciğerlerdeki İçeri Doğrultucu Potasyum Kanalları İfadesi
Project Supported by Higher Education Institutions
DOĞANYİĞİT Z. (Executive), BAŞARAN K. E., YILMAZ S., AKYÜZ E., OKAN OFLAMAZ A., TAHERİ S.
2021 - 2023
2021 - 2023
Ratlardaki Alkol Bağımlılığı Modelinde Kalpteki TRPM2 Katyon Kanallarının MAPK/JNK ve Otofaji Sinyal Yolağı Üzerine Etkinliğinin Araştırılması
Project Supported by Higher Education Institutions
OKAN OFLAMAZ A. (Executive), DOĞANYİĞİT Z., UĞUZ A. C., YILMAZ S.
2021 - 2023
2021 - 2023
Ratlardaki Alkol Bağımlılığı Modelinin Beyindeki Otofajik Yolak Üzerine TRPM2 Katyon Kanallarının Rolü
Project Supported by Higher Education Institutions
OKAN OFLAMAZ A. (Executive), DOĞANYİĞİT Z., UĞUZ A. C., YILMAZ S., ATEŞ Ş.
2021 - 2022
2021 - 2022Rutin'in PI3K / AKT / mTOR sinyal yolunun baskılanması ve bölgeye bağlı protein sentezini düzenleyen argyrofilik nükleolar yoluyla EAC solid tümör üzerindeki antitümöral etkisinin belirlenmesi
Project Supported by Higher Education Institutions
YILMAZ S. (Executive), DOĞANYİĞİT Z., OKAN OFLAMAZ A., ARIKAN E. S.
2021 - 2022
2021 - 2022Sıçanlarda Lipopolisakkarit (LPS) ile oluşturulan endotoksik şok üzerine melatoninin etkilerinin histolojik, immünohistokimyasal ve biyokimyasal yönden araştırılması
Project Supported by Higher Education Institutions
YILMAZ S. (Executive), OKAN OFLAMAZ A., ATEŞ Ş.
2020 - 2022
2020 - 2022
Linagliptin ve insülin kombine tedavisinin tip 1 diyabetik fare kalbindeki katlanmamış protein cevabına olan etkisinin değerlendirilmesi
Project Supported by Higher Education Institutions
DOĞANYİĞİT Z. (Executive), DEMİR N., OKAN OFLAMAZ A., TAHERİ S.
2020 - 2021
2020 - 2021Deneysel Epilepsi Modelinde Endoplazmik Retikulum Stresinin Nöroprotektif Ajanlarla İnhibisyonu
Project Supported by Higher Education Institutions
DOĞANYİĞİT Z. (Executive), TAHERİ S., AKYÜZ E., ATEŞ Ş., YILMAZ S., OKAN OFLAMAZ A.
2015 - 2016
2015 - 20163G Cep Telefonlarından Yayılan Eleketromanyetik Radyasyonun Testis İnterstisial ve Seminifer Tübül Hücrelerinde Endoplazmik Retikulum Stres Yolağı Üzerine Etkisi
Project Supported by Higher Education Institutions
OKAN OFLAMAZ A.
2014 - 2016
2014 - 2016